Picture of Allergin

Allergin

Manufacturer

Afrab-Chem Limited, 22 Abimbola Street, Isolo Industrial Estate, Isolo, Lagos State, Nigeria.

Therapeutic Class

Antihistamines

Dosage Form, Composition & NAFDAC Registration Number (NRN)

  • Tablet (NRN: 04-1288): Chlorpheniramine maleate BP 4 mg.
  • Syrup (NRN: 04-1955): Chlorpheniramine maleate BP 2 mg per 5 mL.

Pack size: 1000 tablets in HDPE Plastic and 60 mL plastic bottle.

Pharmacology

Allergin is an Alkyl amine H-1 receptor antagonist. It diminishes the main action of histamine in the body by competitive reversible blockade of histamine receptor site on tissues. It also possesses anticholinergic and sedative activity. It prevents released histamines from dilating capillaries, thus preventing oedema of the respiratory mucosa.

Indications

Symptomatic control of all allergic conditions responsive to antihistamines including hay fever, vasomotor rhinitis, urticaria, angio-neurotic oedema, food allergy, drug and serum reactions, pruritus, and insect bites.

Contra-indications

  • Allergin should not be given to neonates or premature infants.
  • It should be avoided in pregnancy.
  • It is also contraindicated during attack of asthma.

Precautions/Warnings

  • It should be used with care in conditions such as narrow and acute glaucoma, urinary retention and prostate hypertrophy.
  • Avoid use of Allergin with other products containing Chlorpheniramine maleate.

Interactions

Allergin enhances sedative effect of CNS depressants including alcohol, barbiturates, hypnotics, narcotic analgesics, sedatives and tranquilizers.

Adverse Effects

  • Drowsiness
  • Nausea and
  • Sedation

Dosage and Administration

Allergin is administered orally:

Age                                                Dose

  • Up to 1 year                           2.5 mL 12 hourly.
  • 1 – 5 years(s)                        2.5 – 5 mL hourly.
  • 6 – 12years                           5-10 mL 3 – 4 times daily
  • Adult                                     1 tablet 3-4 times daily

Or as directed by the physician

Storage/Handling Recommendations

  • Keep in a cool dry place and away from the reach of children.