Encapsulators, also called capsule fillers, capsule filling machines or encapsulation machines are mechanical devices commonly used for industrial and pharmaceutical purposes. These machines are used to fill empty soft or hard gelatin capsules of various sizes with powders, granules, semi-solids or liquids substances containing active pharmaceutical ingredients or a mixture of active drug substances and excipients. This process of filling empty capsules with substances is termed encapsulation.
Capsule filling machines should all have the following operating principles in common.
Various types of encapsulation machines are available and these machines are selected based on
Encapsulators used in encapsulation of hard gelatin capsule can be classified or said to be of three types.
These type of encapsulators consists of
A hand operated capsule filling machine is capable of producing about 6250 capsules per hour. This machine is used by small scale manufacturers and hospitals for extempore preparations.
As the name implies, semi-automatic encapsulators (semi-automatic capsule filling machines) combine both manual and automatic methods of capsule filling, thus can be said to be partially automated. Its operation is simple and the equipment meets the hygiene requirements for its use in the pharmaceutical industry.
Its simple design and robust construction (which ensures long life and trouble-free operation), the use of stainless steel and non-corrosive approved materials in the construction of contact parts (which eliminates contamination and facilitates easy cleaning after use) make the machine suitable for filling powders and granular materials in the pharmaceutical and health food industries.
Depending on the design, the following events take place.
Automatic encapsulator is a capsule filling machine that is developed and designed to automatically fill empty hard gelatin capsule with powders and granules. They are used in the large scale production of capsule.
Automatic capsule filling machines are extremely durable and reliable when it comes to capsule filling and maintenance of the integrity of the filled capsules.
Automatic encapsulator can also work as a complete system of fully automatic capsule filling line by attaching additional equipment as online capsule polishing machine, dust extractor, damage capsule sorter and empty capsule ejector.
Kasture P.V., Parakh S.R, Hassan S.A, and Gokhale S.B (2008). Pharmaceutics-1. Fifth edition. Nirali Prakashan, Pune.