Friday, July 23, 2021

How to Reconstitute Injectable Powder for Suspension [Step-By-Step Guide]

by | December 6, 2020 0

Powder for injectable suspension is sterile preparation intended for reconstitution to form a suspension for parenteral use. The dry powder upon the addition of suitable vehicles, yields preparations conforming in all respects to the requirements for injectable suspensions.

Reconstituting a powder medication vial using a diluent in a vial involves the following steps;

Step 1: Determine the type and volume of diluent needed.

Step 2: Choose the appropriate sterile syringe to use when drawing up the diluent and injecting it into the medication vial.

Step 3: Remove the cap from the diluent vial.

Step 4: With an alcohol wipe, clean the top of the diluent vial.

Step 5: Use aseptic technique to draw up the specified amount of diluent.

Step 6: Tap the vial to loosen powder.

Read Also: How to Reconstitute Oral Suspensions [Step-by-Step Guide]

Step 7: Remove the cap the medication vial.

Step 8: With an alcohol wipe, clean the top of the medication vial.

Step 9: Inject the diluent into the powdered medication vial.

Step 10: Agitate the mixture by shaking, inverting, or rolling the vial in your hands – rolling vial will prevent air bubbles to form in the medication.

Step 11: Label vial with your initials (the person who did the reconstitution) and the expiration date and time.

Step 12: Store reconstituted medication according to label directions.

Safety Alert: It is safer not to administer a medication mixed by another health professional. However, if you do, do not administer a medication mixed by the other health professional unless all the appropriate information is on the label, i.e. initials of the person who mixed the medications and expiration date.

Examples of injectable powder for suspension

a. Triamcinolone acetonide injectable suspension

b. Methylprednisolone acetate injectable suspension USP

c. Medroxyprogesterone injection

d. Betamethasone acetate injectable suspension

e. Risperidone extended-release injectable suspension


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