• About Us
  • Contact Us
Saturday, December 7, 2019
Pharmapproach.com
  • Home
  • Post Categories
    • General
    • Interviews
    • Pharma Companies
    • Pharmaceutical Machines
    • Pharmaceutical Technology
    • Pharmacy Practice and Management
  • Forum
No Result
View All Result
Pharmapproach.com
  • Home
  • Post Categories
    • General
    • Interviews
    • Pharma Companies
    • Pharmaceutical Machines
    • Pharmaceutical Technology
    • Pharmacy Practice and Management
  • Forum
No Result
View All Result
Pharmapproach.com
No Result
View All Result

Cutter Mill

by Pharmapproach
July 20, 2019
in Particle Size Reduction Equipment
0
picture of a cutter mill
1
SHARES
1.7k
VIEWS
Share on FacebookShare on Twitter

Cutter mill is a size reduction equipment consisting of a series of uniformly spaced knives (2 to 12 in number) attached to a horizontal rotor (rotating knives) which act against a series of stationary knives attached to the mill casing. The bottom of the mill has a screen attached to control the residence time of the particles inside the mill head.

Size reduction process involves successive mechanical sheering of the feed material with the help of sharp knife. Cutter mills produce coarse particles from

  • Dried granulations before tabletting and
  • Fibrous crude medicinal/roots, barks prior to extraction

 

image of a cutter mill

Particles size are determined by

  • Rotor size
  • The gap between the two (2) sets of knives
  • Screen/sieve

Although cutter mill may differ from one another in whether the knives are movable or fixed and in classifier’s configuration, two cutting mill subclasses have been identified

  • Double runner disc mill
  • Single runner disc mill

Pharmaceutical uses of Cutter Mill  

  • It is used for milling tough materials
  • It is used to mill fibrous materials prior to extraction
  • It is also used to produce coarse particles from dried granulations before tabletting.

Advantages of Cutter Mill

  • It is the best option of size reduction when impaction, attrition or compaction type milling is not effective especially for tough, fibrous or resilient materials.
  • It is easy to install, operate and maintain.
  • The equipment is not expensive

Disadvantages of Cutter Mill

  • Cutter mill is not suitable for most pharmaceutical applications due to the formation of wide particles size.
  • It is not easy to clean after use.

Refereces

  • Ahmed F. Abdel-Magid, and Stéphane Caron (2006). Fundamentals of Early Clinical Drug Development: From Synthesis Design to Formulation. John Wiley and Sons, Inc., Hoboken, New Jersey.
  • http://www.pharmainfo.net/book/pharmaceutical-machines/cutter-mill
  • Martin J. Rhode (2008). Introduction to Particle Technology. John Wiley and Sons Ltd, Chichester, West Sussex, England.
  • Sarfaraz K. Niazi (2009). Handbook of Pharmaceutical Manufacturing Formulations: Semisolid Products. Informa Healthcare USA, Inc., New York.
  • Sud Sushant and Kamath Archana (2013). Methods of Size Reduction and Factors Affecting Size Reduction in Pharmaceutics. International Research Journal of Pharmacy. 4(8): 57-64.

Tags: Milling Equipment
Previous Post

Colloid Mills

Next Post

Edge-Runner Mills and End-Runner Mills

Related Posts

image of a vibration mill
Particle Size Reduction Equipment

Vibration Mill

July 21, 2019
image of a roller mill
Particle Size Reduction Equipment

Roller Mill

July 21, 2019
image of a pin mill
Particle Size Reduction Equipment

Pin Mill

July 21, 2019
Picture of a Hammer mill
Particle Size Reduction Equipment

Hammer Mill

July 20, 2019
image of a fluid energy mill
Particle Size Reduction Equipment

Fluidized Energy Mill

July 20, 2019
image of edge-runner mill and end-runner mill
Particle Size Reduction Equipment

Edge-Runner Mills and End-Runner Mills

July 20, 2019
Next Post
image of edge-runner mill and end-runner mill

Edge-Runner Mills and End-Runner Mills

image of a fluid energy mill

Fluidized Energy Mill

Picture of a Hammer mill

Hammer Mill

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

No Result
View All Result

Popular Posts

  • List of Pharmaceutical Companies in United States of America

    List of Pharmaceutical Companies in the United States of America

    9 shares
    Share 9 Tweet 0
  • Quality Control Tests for Tablets

    7 shares
    Share 5 Tweet 0
  • Manufacture of Pharmaceutical Tablets

    1 shares
    Share 1 Tweet 0
  • Fluidized Bed Dryer

    0 shares
    Share 0 Tweet 0
  • List of Pharmaceutical Companies in Germany

    7 shares
    Share 7 Tweet 0
  • List of Pharmaceutical Companies in India

    4 shares
    Share 4 Tweet 0
  • Roles and Responsibilities of a Finance Department in a Pharmaceutical Industry

    0 shares
    Share 0 Tweet 0
  • List of Pharmaceutical Companies in The United Kingdom

    0 shares
    Share 0 Tweet 0
  • Solid Dosage Forms: Tablets

    2 shares
    Share 2 Tweet 0
  • List of Pharmaceutical Companies in Australia

    0 shares
    Share 0 Tweet 0

Follow Us on Facebook

Follow Us on Facebook

Recent Posts

Featured image for Quality control Tests for capsule Drug Products
Pharmaceutical Technology

Quality Control Tests for Capsule Drug Products

by Pharmapproach
November 28, 2019
0

Capsules are solid dosage forms in which the drug formulation in a powder, solution or suspension, a combination of miscible...

Read more
Featured image for manufacture of soft gelatin capsules

Manufacture of Soft Gelatin Capsules

November 28, 2019
Featured image for soft gelatin capsules

Soft Gelatin Capsules: Formulation and Manufacturing Considerations

November 28, 2019
Medical Terminology

Common Prefixes, Roots and Suffixes in Medical Terminology

October 23, 2019
Pharmaceutical Companies in Canada

List of Pharmaceutical Companies in Canada

November 29, 2019

Regulations, Guidelines and Clinical Trials

Drugs, Chemical and Herbal Regulations
Drugs, Herbal, and Chemical Guidelines
Clinical Trials

Important Links

Drug Manufacturing Companies in Nigeria
National Agency for Food & Drugs Admin & Control
Pharmacists Council of Nigeria
Pharmaceutical Society of Nigeria




Subscribe via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 579 other subscribers

Submit Articles

Click to Submit Your Article

Archives

  • About Us
  • Terms and Conditions
  • Privacy Policy
  • Contact Us

© 2019 Pharmapproach Limited. All Rights Reserved .

No Result
View All Result
  • Home
  • Post Categories
    • General
    • Interviews
    • Pharma Companies
    • Pharmaceutical Machines
    • Pharmaceutical Technology
    • Pharmacy Practice and Management
  • Forum

© 2019 Pharmapproach Limited. All Rights Reserved .

x
This website uses cookies. By continuing to use this website you are giving consent to cookies being used. Visit our Privacy and Cookie Policy.